The respiratory system, which includes air passages, pulmonary vessels, the lungs, and breathing muscles, aids the body in the exchange of gases between the air and blood, and between the blood and the body’s billions of cells. Most of the organs of the respiratory system help to distribute air, but only the tiny, grape-like alveoli and the alveolar ducts are responsible for actual gas exchange.Structure and Function of the Respiratory System Essay Paper

In addition to air distribution and gas exchange, the respiratory system filters, warms, and humidifies the air you breathe. Organs in the respiratory system also play a role in speech and the sense of smell.

The respiratory system also helps the body maintain homeostasis, or balance among the many elements of the body’s internal environment.

The respiratory system is divided into two main components:

Upper respiratory tract: Composed of the nose, the pharynx, and the larynx, the organs of the upper respiratory tract are located outside the chest cavity.

  • Nasal cavity: Inside the nose, the sticky mucous membrane lining the nasal cavity traps dust particles, and tiny hairs called cilia help move them to the nose to be sneezed or blown out.
  • Sinuses: These air-filled spaces along side the nose help make the skull lighter.
  • Pharynx: Both food and air pass through the pharynx before reaching their appropriate destinations. The pharynx also plays a role in speech.
  • Larynx: The larynx is essential to human speech.Structure and Function of the Respiratory System Essay Paper

Lower respiratory tract: Composed of the trachea, the lungs, and all segments of the bronchial tree (including the alveoli), the organs of the lower respiratory tract are located inside the chest cavity.

  • Trachea: Located just below the larynx, the trachea is the main airway to the lungs.
  • Lungs: Together the lungs form one of the body’s largest organs. They’re responsible for providing oxygen to capillaries and exhaling carbon dioxide.
  • Bronchi: The bronchi branch from the trachea into each lung and create the network of intricate passages that supply the lungs with air.
  • Diaphragm: The diaphragm is the main respiratory muscle that contracts and relaxes to allow air into the lungs.

What are the lungs?

Picture of the lungs

The lungs are a pair of organs in the chest that are primarily responsible for the exchange of oxygen and carbon dioxide between the air we breathe and the blood.

What are the symptoms of carbon dioxide poisoning?

  • The cells in the body constantly need a new supply of oxygen to produce energy.
  • With lack of oxygen, cellular function is impaired and damage or cell death may occur.Structure and Function of the Respiratory System Essay Paper
  • As energy is utilized, waste products are created, one of which is the gas carbon dioxide.
  • Eliminating carbon dioxide from the body is just as important as breathing in oxygen from the air.
  • If carbon dioxide builds up in the blood it will lead to headaches, drowsiness, coma, and eventually even death.

    Alveoli: healthy, pneumonia, and emphysema.

    Pneumonia and emphysema are caused by damage to the alveoli of the lungs.Structure and Function of the Respiratory System Essay Paper

What is the structure of the respiratory system?

Air enters the body via the nose (preferably) or the mouth. The air enters the main windpipe, called the trachea, and continues en route to each lung via either the right or left bronchus (plural=bronchi). The lungs are separated into sections called lobes, two on the left and three on the right. The air passages continue to divide into ever smaller tubes, which finally connect with tiny air sacs called alveoli. This gradually branching array of tubes is referred to as the tracheobronchial “tree” because of the remarkable similarity to the branching pattern of a tree.

The other half of the respiratory system involves blood circulation. Venous blood from the body is returned to the right side of the heart and then pumped out via the pulmonary artery. This artery splits in two for the left and right lungs and then continues to branch much like the tracheobronchial tree. These vessels branch into a fine network of very tiny tubes called capillaries. The capillaries are situated adjacent to the alveoli and are so small that only one red blood cell at a time can pass through their openings. It is during this passage that gases are exchanged between the blood and the air in the nearby alveoli. After passing the alveoli, capillaries then join together to begin forming the pulmonary veins, which carry the blood back to the left side of the heart.Structure and Function of the Respiratory System Essay Paper

Lungs Design And Purpose - Illustration

Human Respiratory System

The respiratory system consists of all the organs involved in breathing. These include the nose, pharynx, larynx, trachea, bronchi and lungs. The respiratory system does two very important things: it brings oxygen into our bodies, which we need for our cells to live and function properly; and it helps us get rid of carbon dioxide, which is a waste product of cellular function. The nose, pharynx, larynx, trachea and bronchi all work like a system of pipes through which the air is funneled down into our lungs. There, in very small air sacs called alveoli, oxygen is brought into the bloodstream and carbon dioxide is pushed from the blood out into the air. When something goes wrong with part of the respiratory system, such as an infection like pneumonia, it makes it harder for us to get the oxygen we need and to get rid of the waste product carbon dioxide. Common respiratory symptoms include breathlessness, cough, and chest pain.Structure and Function of the Respiratory System Essay Paper

The respiratory system

The Upper Airway and Trachea

When you breathe in, air enters your body through your nose or mouth. From there, it travels down your throat through the larynx (or voicebox) and into the trachea (or windpipe) before entering your lungs. All these structures act to funnel fresh air down from the outside world into your body. The upper airway is important because it must always stay open for you to be able to breathe. It also helps to moisten and warm the air before it reaches your lungs.Structure and Function of the Respiratory System Essay Paper

The Lungs

Structure
The lungs are paired, cone-shaped organs which take up most of the space in our chests, along with the heart. Their role is to take oxygen into the body, which we need for our cells to live and function properly, and to help us get rid of carbon dioxide, which is a waste product. We each have two lungs, a left lung and a right lung. These are divided up into ‘lobes’, or big sections of tissue separated by ‘fissures’ or dividers. The right lung has three lobes but the left lung has only two, because the heart takes up some of the space in the left side of our chest. The lungs can also be divided up into even smaller portions, called ‘bronchopulmonary segments’.Structure and Function of the Respiratory System Essay Paper
These are pyramidal-shaped areas which are also separated from each other by membranes. There are about 10 of them in each lung. Each segment receives its own blood supply and air supply.
How they work
Air enters your lungs through a system of pipes called the bronchi. These pipes start from the bottom of the trachea as the left and right bronchi and branch many times throughout the lungs, until they eventually form little thin-walled air sacs or bubbles, known as the alveoli. The alveoli are where the important work of gas exchange takes place between the air and your blood. Covering each alveolus is a whole network of little blood vessel called capillaries, which are very small branches of the pulmonary arteries. It is important that the air in the alveoli and the blood in the capillaries are very close together, so that oxygen and carbon dioxide can move (or diffuse) between them. So, when you breathe in, air comes down the trachea and through the bronchi into the alveoli. This fresh air has lots of oxygen in it, and some of this oxygen will travel across the walls of the alveoli into your bloodstream. Travelling in the opposite direction is carbon dioxide, which crosses from the blood in the capillaries into the air in the alveoli and is then breathed out. In this way, you bring in to your body the oxygen that you need to live, and get rid of the waste product carbon dioxide.Structure and Function of the Respiratory System Essay Paper

Alveoli
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Blood Supply
The lungs are very vascular organs, meaning they receive a very large blood supply. This is because the pulmonary arteries, which supply the lungs, come directly from the right side of your heart. They carry blood which is low in oxygen and high in carbon dioxide into your lungs so that the carbon dioxide can be blown off, and more oxygen can be absorbed into the bloodstream. The newly oxygen-rich blood then travels back through the paired pulmonary veins into the left side of your heart. From there, it is pumped all around your body to supply oxygen to cells and organs.

How Does the Respiratory System Work?

Organs specialized for breathing usually contain moist structures with large surface areas to allow the diffusion of gases. They are also adapted to protect the organism from the invasion of pathogens along those surfaces.

In fish, this gas exchange occurs through gills. Some invertebrates, like cockroaches, have simple respiratory systems made of interconnecting tubules directly delivering oxygen to tissues. In humans and other mammals, there is an extensive, highly vascularized organ system specialized for gas exchange.Structure and Function of the Respiratory System Essay Paper

The respiratory system begins in the nose, continues into the pharynx and larynx, leads to the trachea which branch to create bronchi, and finally down the bronchi oles into the lungs. This respiratory tree ends in puffy structures called alveoli that are made of a single layer of squamous cells, surrounded by a network of capillaries. Gas exchange occurs within alveoli. Since external respiration in many vertebrates involves lungs, it is also called pulmonary ventilation. Changes to the volume and pressure in the lungs are the primary driving forces for breathing.

Respiratory System Function

Primary Function

The primary function of the respiratory system is gas exchange. Animal cells use oxygen and produce carbon dioxide as a byproduct. Not only do animals need a way to get more oxygen into the cells, but they also need a way to remove carbon dioxide. The respiratory system provides this functionality. The lungs or gills of an animal remove carbon dioxide while delivering oxygen to the blood. This oxygen is carried to the tissues. The tissues deposit their carbon dioxide waste, which is then carried back to the lungs for release.Structure and Function of the Respiratory System Essay Paper

Creating Sounds

While the primary function of the respiratory system is gas exchange, this extensive organ system also has some other roles. In humans and other mammals, the respiratory system is integral creating sounds such as those used for speech. Structures of the upper respiratory tract, especially the larynx, are involved in the production of sound and can modulate pitch, volume, and clarity. Making noises is called phonation.

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Olfactory Senses

The nose plays an important role in respiration, but the olfactory nerves and their associated structures are also involved in sensing smell. This has functions ranging from digestion (the cephalic phase of digestion) to hunting, recognition, and mating. Most animals have some sort of olfactory senses, usually in the form of nerves within the respiratory system. Sharks, for instance, can smell blood in the water up to several miles away. Terrestrial predators, like wolves, also use their olfactory senses to detect prey.Structure and Function of the Respiratory System Essay Paper

Immunity

The cells of the respiratory tract also protect the body from the invasion of pathogens through the nasal passages. They have an important role in the immune system since the respiratory tract is one of the organ systems with intensive and repeated interaction with the environment (the other is the digestive system). Epithelial cells in the airway can secrete antibodies, defensins and various enzymes and peptides, as well as small oxidative molecules that hamper pathogenic colonization.

In addition, some of these epithelial cells also secrete mucus to trap larger dust particles. The respiratory system plays host to a specialized lymphoid tissue that can produce lymphocytes as a first-line of defense. Coughing and sneezing are other important mechanisms used to fight infections, by removing large quantities of bacteria or viruses trapped in mucus.Structure and Function of the Respiratory System Essay Paper

Other Functions

The cells of the respiratory tract can help in removing clots in pulmonary blood vessels. They also activate hormones and either remove or add to the substances circulating in the blood. They can make incoming air warm and moist, in order to protect the delicate cells of the inner respiratory passages.

Finally, epithelial cells of the lung also produce surfactant that makes the process of inhalation and exhalation easier. In fact, adequate production of surfactant by fetal lung cells is an important prerequisite for viability in pre-term births.

Respiratory System Parts

In humans and most mammals, the anatomy of the respiratory system is divided into three parts. The first is the series of conducting tubes that carry air from the atmosphere towards the lungs. The second part consists of the muscles of respiration – the diaphragm and intercostal muscles in the ribs. The lungs form the third part.

Respiratory System Diagram
Respiratory System Diagram

Muscles of the Respiratory System

The diaphragm is a dome-shaped muscle that curves upwards towards the lungs. When it contracts, it becomes flattened and therefore increases the volume of the thoracic cavity. Similarly, contraction of the external intercostal muscles moves the ribs upwards and outwards. This increase in volume leads to a drop in pressure within the lungs, allowing air to flow passively into the airways. Gas exchange occurs at alveoli till these muscles relax, reversing the process.Structure and Function of the Respiratory System Essay Paper

But, the diaphragm is not alone. The intercostal muscles, as seen in the picture below, provide expansion and contraction of the rib cage, which furthers the movement of air in and out of the lungs.

Thorax zoom
Thorax zoom

Airways of the Respiratory System

The airways can be divided into the conducting and respiratory zones. The conducting zone begins at the nose and ends at smaller bronchioles, and these passages carry air towards the inner recesses of the lungs. The respiratory zone contains the terminal bronchioles and the alveoli – the sites where gas exchange occurs.

The nose and the mouth form the main external openings and mark the beginning of the conducting zone of the airway or respiratory tract. The nasal cavity situated behind the nose contains hair and filters and humidifies air. Most large environmental pollutants are trapped in the mucus secreted by the cells of the nose and nasal cavity. The mouth is unable to reproduce all the functions of the nasal cavity and acts as a second opening when the nose is either blocked or when there is an immediate need for large quantities of air.Structure and Function of the Respiratory System Essay Paper

Air then passes into the pharynx, which is also involved in swallowing. The epiglottis prevents the movement of food into the respiratory tract and the misdirection of air towards the esophagus. When the epiglottis doesn’t function properly, small particles can enter the trachea. These are removed through coughing. If food is lodged or stuck in the airway, it may need to be quickly removed through abdominal thrusts, also known as the Heimlich maneuver.

The larynx follows the pharynx and its main function is the production of sound. The flow of air through this region can influence pitch and volume. Air then enters the trachea, a long tube that is covered by a series of cartilaginous rings, which help this tubular structure retain its shape during inhalation and exhalation. The trachea is lined by pseudostratified columnar epithelia with goblet cells secreting mucins and helping to form mucus.

The Lungs

The trachea splits to form two primary bronchi, called the left and right bronchi. Each of these leads towards a lung and then undergoes repeated branching to produce secondary, tertiary bronchi, and bronchi oles, with successively smaller diameters. When the bronchi oles are less than a millimeter in diameter, they are called terminal bronchi oles, whose purpose is to end in vascularized alveoli. As the bronchi begin to branch, their internal structure changes. Cartilage is more common in the larger airways, and a single epithelial layer is common in the smallest parts of the conducting zone and the respiratory zone. Bronchi and bronchi oles both contain smooth muscles that can constrict in times of rest, or dilate during exercise.Structure and Function of the Respiratory System Essay Paper

Lungs are made of spongy tissue containing many vascular tissues and much of the airway that appears after the trachea. A pleural membrane allows these paired organs to expand and contract with minimal friction. The left lung is smaller than the right due to the location of the heart on the left side of the thoracic cavity.

Respiratory System Structure

The organs described above work as a functional unit within the respiratory system. Air is taken in through the mouth and nose. From here, it makes its way down the trachea. The trachea splits into the bronchi of each lung, where it further divides into a number of smaller tubes that lead to the alveoli. These tiny sacs within the lung are the actual sites of gas exchange.

The alveoli directly contact tiny capillaries from the circulatory system and are able to pass small gas molecules and some waste products across the cell membranes separating them. Oxygen is added to the blood, while carbon dioxide is taken into the alveoli. When the breath is released, this carbon dioxide is released into the atmosphere. The oxygen will make its way via the circulatory system to the tissues, where it will release its oxygen and pick up more carbon dioxide. Thus, the cycle of respiration repeats itself constantly.Structure and Function of the Respiratory System Essay Paper

Diseases of the Respiratory System

Diseases of the respiratory tract can arise due to obstruction to the airway, constriction of the passages, or the loss of the extensive surface area of alveoli for gas exchange. There could also be difficulties with the capillaries surrounding these alveoli, either due to clots or due to altered cardiac function. These illnesses could be chronic conditions or temporary infections. They could also simply be minor changes to the breathing pattern, as seen with hiccups.

Common Cold

The common cold, appropriately named for its ubiquitous nature is caused by a large number of different viruses, with rhinoviruses being the most varied and common cause for this complaint. It is usually an infection of the upper respiratory tract, though it can occasionally spread towards the ears, or the lower respiratory structures as well. The infection is transmitted through direct contact with the infected person, especially their nasal discharges.Structure and Function of the Respiratory System Essay Paper

This is particularly difficult to prevent since a person is infectious before they begin to show symptoms. The viruses usually establish contact with the cells of the nose, which then produce a clear liquid to trap these microorganisms and expel them from the body. This is followed by sneezing and coughing, especially if the virus travels deeper into the airway. Thick, yellow or green sputum being coughed is a sign of these microbes being attacked by the host’s immune system. Antibiotics are useless against viral infections and the symptoms usually subside after a week.

Tuberculosis

On the other end of the spectrum of infectious diseases of the respiratory tract is tuberculosis, or TB. It is a bacterial infection caused by Mycobacterium tuberculosis and until the advent of powerful antibiotics, could often lead to death after a painful illness. The infection spreads by the transmission of live bacteria from the infected person, especially through oral and nasal discharges. Since the bacterium is hardy and can exist in a desiccated form for many months, the illness can quickly reach epidemic proportions in regions where population density is high, or there is a prolonged cold season where people stay indoors and interact closely with one another. Many healthy children and adults can overcome an infection without obvious symptoms, where only a blood test can confirm that an infection has occurred.Structure and Function of the Respiratory System Essay Paper

The disease is named after the hard nodules that form within the lungs, called tubercles. These tubercles can not only erode respiratory tissue, but they can also attack the blood vessels, leading to the patient coughing up blood. This is a dramatic symptom indicative of an advanced stage of the disease. The advent of HIV and AIDS brought tuberculosis to the forefront, with the original tubercles of a resolved infection breaking down and releasing bacteria into the bloodstream. Immunocompromised individuals, whether infants, the elderly, or those with autoimmune diseases, become susceptible to the recurrence of this ailment. Treatment usually involves multiple antibiotics over an extended period of time. Caregivers need to be vaccinated.

Lung Cancer

Lung cancer is the development of a malignant tumor in the lungs, associated with uncontrolled cell growth within the tissues and the metastasis of these cells to other organs within the body. Smoking, especially when begun at an earlier age, is the highest risk factor for developing lung cancer. Passive smoking is often equally dangerous. In recent history, King George VI died of complications relating to lung cancer, brought on by years of heavy smoking. Though tobacco smoking accounts for over 80% of lung cancer cases, any chemical substance that repeatedly irritates the delicate inner linings of the lung can lead to the formation of a tumor. These include asbestos, chromium, nickel, radon gas, uranium dust, coal dust. The most common organ for the metastasis of lung cancer is the bone. Therefore advanced stages of the disease also involve pain in the bones.Structure and Function of the Respiratory System Essay Paper

Alveoli are an important part of the respiratory system whose function it is to exchange oxygen and carbon dioxide molecules to and from the bloodstream. These tiny, balloon-shaped air sacs sit at the very end of the respiratory tree and are arranged in clusters throughout the lungs.

Structure

Alveoli are tiny balloon shaped structures and are the smallest passageway in the respiratory system. The alveoli are only one cell thick, allowing the relatively easy passage of oxygen and carbon dioxide (CO2) between the alveoli and blood vessels called capillaries.

One cubic millimeter of lung tissue contains around 170 alveoli. While the total number can vary from one person to the next, there are literally millions within the human lungs spanning a surface area of roughly 70 square meters.

Function

Alveoli are the endpoint of the respiratory system which starts when we inhale air into the mouth or nose. The oxygen-rich air travels down the trachea and then into one of the two lungs via the right or left bronchus. From there, the air is directed through smaller and smaller passages, called bronchi oles, past the alveolar duct, until it finally enters an individual alveolus.Structure and Function of the Respiratory System Essay Paper

Alveoli are lined by a fluid layer known as a surfactant which maintains the shape and surface tension of the air sac. By maintaining surface tension, there is more surface area through which oxygen and CO2 molecules can pass.

It is at this junction that oxygen molecules diffuse through a single cell in an alveolus and then a single cell in a capillary to enter the bloodstream. At the same time, CO2 molecules, a byproduct of cellular respiration, are diffused back into alveolus where they are expelled out of the body through the nose or mouth.

During inhalation, capillaries expand as the negative pressure in the chest is created by contraction of the diaphragm. During exhalation, the alveoli recoil (spring back) as the diaphragm relaxes.

Medical Conditions Affecting Alveoli

There are a number of medical conditions that can directly affect the alveoli (that we refer to as alveolar lung diseases). These diseases can cause the alveoli can become inflamed and scarred or cause them to fill with water, pus, or blood.

Among the conditions involving the alveoli:

  • Emphysema is a condition in which the inflammation in the lungs causes the dilation and destruction of alveoli. In addition to the loss of alveoli, the cellular walls of air sacs begin to harden and lose their elasticity. This makes it difficult to expel air from the lungs (a condition called air trapping). This explains why exhaling rather than inhaling is usually more difficult in people with emphysema. This inability to expel air leads to further dilatation of the alveoli and the increased loss of function
  • Pneumonia is an infection that inflames the alveoli in one or both lungs and can result in the air sacs filling with pus.Structure and Function of the Respiratory System Essay Paper
  • Tuberculosis is an infectious bacterial disease characterized by the growth of nodules in the tissues of the lungs. The disease primarily infects the alveoli as bacteria are inhaled, causing the formation of pus in the air sacs.
  • Bronchioloalveolar carcinoma (BAC) is a form of lung cancer that is now instead considered a subtype of lung adenocarcinoma. These cancers begin in the alveoli and are often found diffusely in one or both lungs.
  • Acute respiratory distress syndrome (ARDS) is a life-threatening lung condition that prevents oxygen from getting to the lungs as fluids begin to accumulate in the alveoli. ARDS is common in critically ill patients.
  • Respiratory distress syndrome (RDS) is seen in premature babies whose bodies have not yet produced enough surfactant to line the alveoli.
  • Pulmonary edema is a condition caused by excess fluid in the lungs which collect in the alveoli and can lead to respiratory failure.

Cigarettes and Alveoli

As a single risk factor for lung disease, tobacco smoke is known to affect the respiratory tract at every level. This includes the alveoli.Structure and Function of the Respiratory System Essay Paper

Alveoli are made up of collagen and elastin which provide the sacs their elasticity. Smoking damages both of these, causing the sacs to harden and thicken. Smoking also actively dilates blood vessels, impeding the exchange of oxygen and CO2.

Cigarette smoke also affects how the alveoli work, causing damage right down to the molecular level. It disrupts our body’s ability to repair itself as it might following an infection or trauma. As such, the alveolar damage is allowed to progress unhindered as the lungs are persistently exposed to toxic fumes.

A Word From Very well

The alveoli provide one of the most important functions our bodies perform. They’re the gateway through which oxygen enters our bloodstream and the primary way in which some of the waste products of metabolism (carbon dioxide) exit the body.Structure and Function of the Respiratory System Essay Paper

Diseases which affect the alveoli can result in reduced oxygen being delivered to the tissues of our body, and consequently, may result in damage (due to hypoxia) to every major organ.Structure and Function of the Respiratory System Essay Paper